Osteoarthritis is not just simple “wear and tear” of joints, but a complex, inflammatory disease that starts with a joint injury. This injury disturbs the natural balance between building up and breaking down cartilage, leading to a damaging cycle known as “Tear, Flare, and Repair.”
After an injury or even normal “wear and tear”, inflammation occurs (the “Flare”) with the release of harmful substances from cartilage, bone, and the joint lining that both damage tissue and interfere with their repair. The attempt to repair that damage (the “Repair”) is often too quick and not thorough enough, failing to fix the cartilage properly and leaving it weak and more likely to get injured again.
This leads to a harmful loop of inflammation, cartilage damage, and poor repair, causing the pain, stiffness, and restricted movement common in osteoarthritis.
Understanding this process is key to finding treatments that not only ease symptoms but also tackle the underlying causes of the disease.
The process of cartilage remodelling is central to treating osteoarthritis because it involves both the breakdown and rebuilding of cartilage. Ideally, these processes are balanced. However, in osteoarthritis, the breakdown exceeds the rebuilding, leading to the gradual deterioration of joint health.
By focusing on the cartilage remodelling process, researchers aim to develop treatments that can restore this balance – either by enhancing the body’s ability to repair and regenerate cartilage or by reducing the rate of cartilage breakdown.
Such targeted treatments could potentially slow the progression of osteoarthritis, relieve symptoms, and improve joint function, making them a critical area of focus in research and therapy.
Current treatments for osteoarthritis, like painkillers and anti-inflammatory drugs, only manage symptoms without targeting the disease’s progression.
Conventional supplements, such as glucosamine and chondroitin, have shown limited benefits.
LithoLexal® JOINT-FLEX PRO does more than just relieve symptoms — it addresses the underlying causes of osteoarthritis, like inflammation and cartilage breakdown, to reduce pain, normalise the cartilage remodelling cycle and fundamentally alter the course of osteoarthritis.
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